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1.

Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology.

Benson, Al B; Venook, Alan P; Al-Hawary, Mahmoud M; Azad, Nilofer; Chen, Yi-Jen; Ciombor, Kristen K; Cohen, Stacey; Cooper, Harry S; Deming, Dustin; Garrido-Laguna, Ignacio; Grem, Jean L; Hecht, J Randolph; Hoffe, Sarah; Hubbard, Joleen; Hunt, Steven; Hussan, Hisham; Jeck, William; Johung, Kimberly L; Joseph, Nora; Kirilcuk, Natalie; Krishnamurthi, Smitha; Maratt, Jennifer; Messersmith, Wells A; Meyerhardt, Jeffrey; Miller, Eric D; Mulcahy, Mary F; Nurkin, Steven; Overman, Michael J; Parikh, Aparna; Patel, Hitendra; Pedersen, Katrina; Saltz, Leonard; Schneider, Charles; Shibata, David; Skibber, John M; Sofocleous, Constantinos T; Stotsky-Himelfarb, Eden; Tavakkoli, Anna; Willett, Christopher G; Williams, Grant; Algieri, Frankie; Gurski, Lisa; Stehman, Katie.

J Natl Compr Canc Netw; 21(6): 653-677, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37308125

2.

Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.

Benson, Al B; Venook, Alan P; Al-Hawary, Mahmoud M; Azad, Nilofer; Chen, Yi-Jen; Ciombor, Kristen K; Cohen, Stacey; Cooper, Harry S; Deming, Dustin; Garrido-Laguna, Ignacio; Grem, Jean L; Gunn, Andrew; Hecht, J Randolph; Hoffe, Sarah; Hubbard, Joleen; Hunt, Steven; Jeck, William; Johung, Kimberly L; Kirilcuk, Natalie; Krishnamurthi, Smitha; Maratt, Jennifer K; Messersmith, Wells A; Meyerhardt, Jeffrey; Miller, Eric D; Mulcahy, Mary F; Nurkin, Steven; Overman, Michael J; Parikh, Aparna; Patel, Hitendra; Pedersen, Katrina; Saltz, Leonard; Schneider, Charles; Shibata, David; Skibber, John M; Sofocleous, Constantinos T; Stotsky-Himelfarb, Eden; Tavakkoli, Anna; Willett, Christopher G; Gregory, Kristina; Gurski, Lisa.

J Natl Compr Canc Netw; 20(10): 1139-1167, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-36240850

3.

Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC).

Hecht, J Randolph; Papadopoulos, Kyriakos P; Falchook, Gerald S; Patel, Manish R; Infante, Jeffrey R; Aljumaily, Raid; Wong, Deborah J; Autio, Karen A; Wainberg, Zev A; Bauer, Todd M; Javle, Milind; Pant, Shubham; Bendell, Johanna; Hung, Annie; Ratti, Navneet; VanVlasselaer, Peter; Verma, Rakesh; Leveque, Joseph; Rao, Sujata; Oft, Martin; Naing, Aung.

Invest New Drugs; 39(1): 182-192, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-32910338

4.

Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

Benson, Al B; Venook, Alan P; Al-Hawary, Mahmoud M; Arain, Mustafa A; Chen, Yi-Jen; Ciombor, Kristen K; Cohen, Stacey; Cooper, Harry S; Deming, Dustin; Farkas, Linda; Garrido-Laguna, Ignacio; Grem, Jean L; Gunn, Andrew; Hecht, J Randolph; Hoffe, Sarah; Hubbard, Joleen; Hunt, Steven; Johung, Kimberly L; Kirilcuk, Natalie; Krishnamurthi, Smitha; Messersmith, Wells A; Meyerhardt, Jeffrey; Miller, Eric D; Mulcahy, Mary F; Nurkin, Steven; Overman, Michael J; Parikh, Aparna; Patel, Hitendra; Pedersen, Katrina; Saltz, Leonard; Schneider, Charles; Shibata, David; Skibber, John M; Sofocleous, Constantinos T; Stoffel, Elena M; Stotsky-Himelfarb, Eden; Willett, Christopher G; Gregory, Kristina M; Gurski, Lisa A.

J Natl Compr Canc Netw; 19(3): 329-359, 2021 03 02.

Artículo en Inglés | MEDLINE | ID: mdl-33724754

5.

Meta-analysis examining overall survival in patients with pancreatic cancer treated with second-line 5-fluorouracil and oxaliplatin-based therapy after failing first-line gemcitabine-containing therapy: effect of performance status and comparison with other regimens.

Wainberg, Zev A; Feeney, Kynan; Lee, Myung Ah; Muñoz, Andrés; Gracián, Antonio Cubillo; Lonardi, Sara; Ryoo, Baek-Yeol; Hung, Annie; Lin, Yong; Bendell, Johanna; Hecht, J Randolph.

BMC Cancer; 20(1): 633, 2020 Jul 08.

Artículo en Inglés | MEDLINE | ID: mdl-32641104

6.

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers.

Diaz, Luis A; Williams, Richard T; Wu, Jian; Kinde, Isaac; Hecht, J Randolph; Berlin, Jordan; Allen, Benjamin; Bozic, Ivana; Reiter, Johannes G; Nowak, Martin A; Kinzler, Kenneth W; Oliner, Kelly S; Vogelstein, Bert.

Nature; 486(7404): 537-40, 2012 Jun 28.

Artículo en Inglés | MEDLINE | ID: mdl-22722843

7.

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma.

Hecht, J Randolph; Benson, Al B; Vyushkov, Dmitry; Yang, Yingsi; Bendell, Johanna; Verma, Udit.

Oncologist; 22(3): 243-e23, 2017 03.

Artículo en Inglés | MEDLINE | ID: mdl-28246207

8.

A Phase II Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First-Line Treatment of Pancreatic Adenocarcinoma.

Benson, Al B; Wainberg, Zev A; Hecht, J Randolph; Vyushkov, Dmitry; Dong, Hua; Bendell, Johanna; Kudrik, Fred.

Oncologist; 22(3): 241-e15, 2017 03.

Artículo en Inglés | MEDLINE | ID: mdl-28246206

9.

Final analysis of the randomised PEAK trial: overall survival and tumour responses during first-line treatment with mFOLFOX6 plus either panitumumab or bevacizumab in patients with metastatic colorectal carcinoma.

Rivera, Fernando; Karthaus, Meinolf; Hecht, J Randolph; Sevilla, Isabel; Forget, Frédéric; Fasola, Gianpiero; Canon, Jean-Luc; Guan, Xuesong; Demonty, Gaston; Schwartzberg, Lee S.

Int J Colorectal Dis; 32(8): 1179-1190, 2017 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-28424871

10.

A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results.

Rappaport, Amy R; Kyi, Chrisann; Lane, Monica; Hart, Meghan G; Johnson, Melissa L; Henick, Brian S; Liao, Chih-Yi; Mahipal, Amit; Shergill, Ardaman; Spira, Alexander I; Goldman, Jonathan W; Scallan, Ciaran D; Schenk, Desiree; Palmer, Christine D; Davis, Matthew J; Kounlavouth, Sonia; Kemp, Lindsey; Yang, Aaron; Li, Yaojun John; Likes, Molly; Shen, Annie; Boucher, Gregory R; Egorova, Milana; Veres, Robert L; Espinosa, J Aaron; Jaroslavsky, Jason R; Kraemer Tardif, Lauren D; Acrebuche, Lindsey; Puccia, Christopher; Sousa, Leiliane; Zhou, Rita; Bae, Kyounghwa; Hecht, J Randolph; Carbone, David P; Johnson, Benny; Allen, Andrew; Ferguson, Andrew R; Jooss, Karin.

Nat Med; 30(4): 1013-1022, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38538867

11.

Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial.

de Gramont, Aimery; Van Cutsem, Eric; Schmoll, Hans-Joachim; Tabernero, Josep; Clarke, Stephen; Moore, Malcolm J; Cunningham, David; Cartwright, Thomas H; Hecht, J Randolph; Rivera, Fernando; Im, Seock-Ah; Bodoky, György; Salazar, Ramon; Maindrault-Goebel, Frédérique; Shacham-Shmueli, Einat; Bajetta, Emilio; Makrutzki, Martina; Shang, Aijing; André, Thierry; Hoff, Paulo M.

Lancet Oncol; 13(12): 1225-33, 2012 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-23168362

12.

Next-Generation Approaches to Immuno-Oncology in GI Cancers.

Hecht, J Randolph; Mitchell, Jasmine; Morelli, Maria Pia; Anandappa, Gayathri; Yang, James C.

Am Soc Clin Oncol Educ Book; 43: e389072, 2023 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-37290032

13.

Fecal and Tissue Microbiota Are Associated with Tumor T-Cell Infiltration and Mesenteric Lymph Node Involvement in Colorectal Cancer.

Luu, Kayti; Ye, Jason Y; Lagishetty, Venu; Liang, Fengting; Hauer, Megan; Sedighian, Farzaneh; Kwaan, Mary R; Kazanjian, Kevork K; Hecht, J Randolph; Lin, Anne Y; Jacobs, Jonathan P.

Nutrients; 15(2)2023 Jan 09.

Artículo en Inglés | MEDLINE | ID: mdl-36678187

14.

Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy.

Wainberg, Zev A; Singh, Arun S; Konecny, Gottfried E; McCann, Kelly E; Hecht, J Randolph; Goldman, Jonathan; Chmielowski, Bartosz; Finn, Richard S; O'Brien, Neil; Von Euw, Erika; Price, Megan M; Martinez, Diego; Yonemoto, Lisa; Brennan, Meghan; Glaspy, John A; Slamon, Dennis J.

Clin Cancer Res; 29(1): 40-49, 2023 01 04.

Artículo en Inglés | MEDLINE | ID: mdl-36136304

15.

Evaluation of Intratumoral Response Heterogeneity in Metastatic Colorectal Cancer and Its Impact on Patient Overall Survival: Findings from 10,551 Patients in the ARCAD Database.

Ou, Fang-Shu; Ahn, Daniel H; Dixon, Jesse G; Grothey, Axel; Lou, Yiyue; Kasi, Pashtoon M; Hubbard, Joleen M; Van Cutsem, Eric; Saltz, Leonard B; Schmoll, Hans-Joachim; Goldberg, Richard M; Venook, Alan P; Hoff, Paulo; Douillard, Jean-Yves; Hecht, J Randolph; Hurwitz, Herbert; Punt, Cornelis J A; Koopman, Miriam; Bokemeyer, Carsten; Fuchs, Charles S; Diaz-Rubio, Eduardo; Tebbutt, Niall C; Cremolini, Chiara; Kabbinavar, Fairooz F; Bekaii-Saab, Tanios; Chibaudel, Benoist; Yoshino, Takayuki; Zalcberg, John; Adams, Richard A; de Gramont, Aimery; Shi, Qian.

Cancers (Basel); 15(16)2023 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-37627145

16.

EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study.

Hecht, J Randolph; Farrell, James J; Senzer, Neil; Nemunaitis, John; Rosemurgy, Alexander; Chung, Theodore; Hanna, Nader; Chang, Kenneth J; Javle, Milind; Posner, Mitchell; Waxman, Irving; Reid, Anthony; Erickson, Richard; Canto, Marcia; Chak, Amitabh; Blatner, Gretta; Kovacevic, Milan; Thornton, Mark.

Gastrointest Endosc; 75(2): 332-8, 2012 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-22248601

17.

VISUAL VIGNETTE.

Yu, Run; Quon, Andrew; Hecht, J Randolph.

Endocr Pract; 23(10): 1276, 2017 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-28332878

18.

Familial Duodenal Somatostatinomatosis Not Associated With a Known Genetic Syndrome.

Yu, Run; Rao, Jianyu; Zhai, Jing; Hecht, J Randolph; Pisegna, Joseph R.

Pancreas; 51(8): 1056-1060, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-36607953

19.

A Randomized Phase II Study of Nivolumab Monotherapy or Nivolumab Combined with Ipilimumab in Patients with Advanced Gastrointestinal Stromal Tumors.

Singh, Arun S; Hecht, J Randolph; Rosen, Lee; Wainberg, Zev A; Wang, Xiaoyan; Douek, Michael; Hagopian, Anahis; Andes, Rachel; Sauer, Lauren; Brackert, Sandra R; Chow, Warren; DeMatteo, Ronald; Eilber, Fritz Christian; Glaspy, John A; Chmielowski, Bartosz.

Clin Cancer Res; 28(1): 84-94, 2022 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-34407970

20.

Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips.

Sun, Na; Yang, Yingying; Miao, Hui; Redublo, Peter; Liu, Hongtao; Liu, Wenfei; Huang, Yen-Wen; Teng, Pai-Chi; Zhang, Ceng; Zhang, Ryan Y; Smalley, Matthew; Yang, Peng; Chou, Shih-Jie; Huai, Kevin; Zhang, Zhicheng; Lee, Yi-Te; Wang, Jasmine J; Wang, Jing; Liang, Icy Y; Zhang, Tiffany X; Zhang, Dongyun; Liang, Li; Weiss, Paul S; Posadas, Edwin M; Donahue, Timothy; Hecht, J Randolph; Allen-Auerbach, Martin S; Bergsland, Emily K; Hope, Thomas A; Pei, Renjun; Zhu, Yazhen; Tseng, Hsian-Rong; Heaney, Anthony P.

Biosens Bioelectron; 199: 113854, 2022 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-34896918

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